Organism:
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Klebsiella pneumoniae subsp. pneumoniae (Schroeter) Trevisan deposited as Klebsiella pneumoniae (Schroeter) Trevisan
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Designations:
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K6 [CCUG 45421, LMG 20218, MCV37]
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Isolation:
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urine from hospitalized patient, Richmond, VA, 1994 [110814]
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Depositor:
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JM Swenson
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History:
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ATCC <<--JM Swenson<<--M.J. Ferraro <<-- G. Jacoby <<-- H. Dalton
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Biosafety Level:
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2
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Shipped:
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freeze-dried
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Growth Conditions:
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ATCC medium3: Nutrient agar or nutrient broth
Temperature: 37.0°C
Duration: aerobic
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Permits/Forms:
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In addition to the MTA mentioned above, other ATCC and/or regulatory permits may be required for the transfer of this ATCC material. Anyone purchasing ATCC material is ultimately responsible for obtaining the permits. Please click here for information regarding the specific requirements for shipment to your location.
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Cross References:
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Nucleotide (GenBank) : AF132290 Klebsiella pneumoniae plasmid-encoded extended-spectrum beta-lactamase (bla SHV-18) gene, complete cds.
Nucleotide (GenBank) : AX111170 Sequence 1903 from Patent WO0123604.
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Comments:
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MIC (ug/ml): Ampicillin >64; Amoxicillin-clavulanate 8; Aztreonam 64; Aztreonam-clavulanate <=0.25; Cefotaxime 8; Cefotaxime-clavulanate <=0.25; Cefpodoxime 16; Cefpodoxime-clavulanate 1; Ceftazidime 32 [49425]
MIC (ug/ml): Ceftazidime-clavulanate 1; Ceftriaxone 16; Ceftriaxone-clavulanate <=0.25; Cefepime 1; Cefoxitin 32; Chloramphenicol >32; Ciprofloxacin 0.5; Gentamicin 8 [49425]
MIC (ug/ml): Imipenem <=1; Piperacillin >128; Piperacillin-tazobactam 16; Tetracycline 16; Tobramycin 4; Trimethoprim-sulfamethoxazole 2 [49425]
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Applications:
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produces beta-lactamase SHV-18 [49425]
quality control strain [92137] [92160]
resistant to ampicillin [49425]
resistant to aztreonam [49425]
resistant to cefoxitin [49425]
resistant to cefpodoxime [49425]
resistant to ceftazidime [49425]
resistant to chloramphenicol [49425]
resistant to piperacillin [49425]
resistant to tetracycline [49425]
sensitive to amoxicillin-clavulanate [49425]
sensitive to cefepime [49425]
sensitive to cefotaxime [49425]
sensitive to ciprofloxacin [49425]
sensitive to imipenem [49425]
sensitive to piperacillin-tazobactam [49425]
sensitive to tobramycin [49425]
sensitive to trimethoprim-sulfamethoxazole [49425]
susceptibility disc testing [21523]
susceptibility testing [21525] [21533] [90283] [92219]
intermediate resistance to ceftriaxone and gentamicin [49425]
control for extended-spectrum beta-lactamase production [49425]
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Related Products:
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purified DNA: ATCC 700603D-5
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References:
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21523: CLSI Performance Standards for Antimicrobial Disk Susceptibility Tests; Approved Standard - 9th Edition. Wayne, PA:Clinical and Laboratory Standards Institute;CLSI M2-A9.
21525: CLSI Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria that Grow Aerobically; Approved Standard - 7th Edition. Wayne, PA:Clinical and Laboratory Standards Institute;CLSI M7-A7.
21533: CLSI Performance Standards for Antimicrobial Disk and Dilution Susceptibility Tests for Bacteria Isolated from Animals; Approved Standard - 2nd Edition. Wayne, PA:Clinical and Laboratory Standards Institute;CLSI M31-A2.
49425: Rasheed JK, et al. Characterization of the extended-spectrum beta-lactamase reference strain, Klebsiella pneumoniae K6 (ATCC 700603), which produces the novel enzyme SHV-18. Antimicrob. Agents Chemother. 44: 2382-2388, 2000. PubMed: 10952583
90283: CLSI Performance Standards for Antimicrobial Susceptibility Testing; Sixteenth Informational Supplement. Wayne, PA:Clinical and Laboratory Standards Institute;CLSI M100-S17, 2007
92137: BD Phoenix Gram Negative NMIC and NMIC/ID. :BD Becton Dickinson;Phoenix
92160: Sensititre MIC Susceptibility. :Trek Diagnostic Systems;Sensititre
92219: CLSI Performance Standards for Antimicrobial Disk and Dilution Susceptibility Tests for Bacteria Isolated from Animals; Informational Supplement. Wayne, PA:Clinical and Laboratory Standards Institute;CLSI M31-S1.
110814: Jana M Swenson, personal communication
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